917235-47-3Relevant academic research and scientific papers
Synthesis of 6-amino-, 6-methyl- and 6-aryl-2-(hydroxymethyl)purine bases and nucleosides
Silhar, Peter,Pohl, Radek,Votruba, Ivan,Klepetarova, Blanka,Hocek, Michal
, p. 788 - 803 (2008/02/02)
An efficient methodology of the synthesis of 6-substituted 2-(hydroxymethyl)purine derivatives (bases and nucleosides) was developed. Regioselective Pd-catalyzed cross-coupling reactions of 6-chloro-2-iodopurines with [(benzoyloxy)methyl]zinc iodide gave
Synthesis of 2-substituted 6-(hydroxymethyl)purine bases and nucleosides
Silhar, Peter,Pohl, Radek,Votruba, Ivan,Hocek, Michal
, p. 1669 - 1695 (2007/10/03)
A facile and efficient methodology of the synthesis of 6-(hydroxymethyl) purine derivatives (bases and nucleosides) was developed based on Pd-catalyzed cross-coupling reactions of 6-halopurines or N-protected 2-amino-6-halopurines with (benzoyloxymethyl)z
