917356-74-2

Upstream product

• 917356-68-4 4'-{[(3R)-3-(4-fluoro-piperidin-1-yl)pyrrolidin-1-yl]sulfonyl}biphenyl-4-carbonitrile 
• 917357-28-9 4'-{[3-(4-fluoro-piperidin-1-yl)pyrrolidin-1-yl]sulfonyl}biphenyl-4-carbonitrile 
• 57395-89-8 4-fluoropiperidine hydrochloride 
• 78197-27-0 4-fluoropiperidine 

Relevant academic research and scientific papers

INHIBITORS OF 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1

The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salts or solvates thereof, wherein n, X, Y, R1, R2, R3 and R4 are as described in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating conditions that are mediated by the modulation of 11 βHSD1 , the method comprising administering to a mammal an effective amount of a compound of formula (I).