917482-82-7Relevant academic research and scientific papers
Oligonucleotides containing pyrazolo[3,4-d]pyrimidines: 8-aza-7-deazaadenines with bulky substituents in the 2- or 7-position
Seela, Frank,Jawalekar, Anup M.,Sun, Lijuan,Leonard, Peter
, p. 1485 - 1505 (2005)
□ The synthesis of the 2′-deoxyadenosine analogues 1b, 2b, and 3c modified at the 7- and/or 2-position is described. The effect of 7-chloro and 2-methylthio groups on the duplex stability is evaluated. For that, the nucleosides 1b, 2b, and 3c were convert
