917494-83-8

Basic information

• Product Name: 1-(4-fluorophenyl)-1H-indazole-5-carbaldehyde
• Synonyms: 1-(4-fluorophenyl)-1H-indazole-5-carbaldehyde
• CAS NO: 917494-83-8
• Molecular Weight: 240.237
• Mol File: 917494-83-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(4-fluorophenyl)-1H-indazole-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-fluorophenyl)-1H-indazole-5-carbaldehyde(917494-83-8)
• EPA Substance Registry System: 1-(4-fluorophenyl)-1H-indazole-5-carbaldehyde(917494-83-8)

Safety Data

• Hazardous Substances Data: 917494-83-8(Hazardous Substances Data)

Upstream product

• 861905-19-3 5-bromo-1-(4-fluorophenyl)-1H-indazole 
• 201230-82-2 carbon monoxide 
• 1025762-58-6 (1-(4-fluorophenyl)-1H-indazol-5-yl)methanol 
• 917484-67-4 1-(4-fluorophenyl)-1H-indazole-5-carbonitrile 

Downstream Products

• 1025762-67-7 methyl 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-3-hydroxy-2,2-dimethylpropanoate 
• 1025762-60-0 (1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methanol 
• 1025762-89-3 1-(1-(4-fluorophenyl)-1H-indazol-5-yl)propan-1-ol 
• 1025762-84-8 cyclohexyl(1-(4-fluorophenyl)-1H-indazol-5-yl)methanol 
• 1025763-03-4 (E)-methyl 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)acrylate 
• 1025763-88-5 4-((1-(4-fluorophenyl)-1H-indazol-5-yl)(hydroxy)methyl)benzonitrile 
• 1025762-72-4 1-(1-(4-fluorophenyl)-1H-indazol-5-yl)-3-methylbutan-1-ol 
• 1025762-75-7 cyclopentyl(1-(4-fluorophenyl)-1H-indazol-5-yl)methanol 
• 1025762-79-1 (1-(4-fluorophenyl)-1H-indazol-5-yl)(pyridin-4-yl)methanol 
• 1025763-64-7 1-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylethanol 
• 1242430-32-5 C₂₀H₁₃Cl₂FN₂O 
• 1242430-71-2 C₁₉H₁₃ClFN₃O 
• 1242430-30-3 C₂₀H₁₄ClFN₂O 
• 1242430-35-8 C₂₀H₁₄F₂N₂O 

Relevant articles and documents

5-Functionalized indazoles as glucocorticoid receptor agonists

An indazole based series of glucocorticoid receptor agonists is reported. The SAR exploration of this scaffold yielded compounds with nanomolar affinity for the glucocorticoid receptor with indications of selectivity for the preferred transrepression mech

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Novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity including inflammatory and immune diseases, obesity and diabetes having the structure of formula (I), its enantiomers, diastereomers, or a pharmaceutically acceptable salt, or hydrate, thereof, wherein X is (Ia); or X is (Ib); or X is (Ic); (Id) is heterocycle or heteroaryl; E is -N-, -NR1-, -O-, -S-, -SO2- or -CR2-; F is -N-, -NR1a-, -O-, -S-, SO2- or -CR2a-; G is N, -NR1b-, -O-, -S-, SO2- or -CR2b-, provided that the E-F-G containing heterocyclic ring formed does not contain a S-S or S-O bond, and at least one of E, F and G is a heteroatom; J, Ja, M, Ma, Q, Rx, Ry, R1, R1a, R1b, R2, R2a, R2b, and R3 to R21, Z, Za, Zb, and Zc are as defined above.