91757-57-2Relevant academic research and scientific papers
The Reaction of 2-Indolecarbohydrazones With Ethixycarbonyl Chloride. New Synthesis of 2,3-Dihydro-2-oxo-1,3,4-oxadiazoles and 1,2,3,4-Tetrahydro-4-oxo-5H-pyridazinoindoles
Monge, A.,Palop, J. A.,Tabar, P.,Fernandez-Alvarez, E.
, p. 397 - 400 (2007/10/02)
The synthesis of 2,3-dihydro-2-oxo-1,3,4-oxadiazole (4) and 5H-pyridazinoindole (7), are described.Compounds 4 were obtained by reduction of O-ethoxycarbonylcarbohydrazones 3 with sodium borohydride.Compounds 7 were obtained by cyclization of compounds with ethanol/hydrochloric acid and removing the ethoxycarbonyl group with hydrazine.Compounds 3 were obtained by reaction of 2-indolecarbohydrazones 1 with ethoxycarbonyl chloride.
