917599-69-0

Basic information

• Product Name: Cbz-L-propargylglycine-Gly-NH₂
• Synonyms: Cbz-L-propargylglycine-Gly-NH₂
• CAS NO: 917599-69-0
• Molecular Weight: 303.318
• Mol File: 917599-69-0.mol

Chemical Properties

• CAS DataBase Reference: Cbz-L-propargylglycine-Gly-NH₂(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-L-propargylglycine-Gly-NH₂(917599-69-0)
• EPA Substance Registry System: Cbz-L-propargylglycine-Gly-NH₂(917599-69-0)

Safety Data

• Hazardous Substances Data: 917599-69-0(Hazardous Substances Data)

Upstream product

• 869116-13-2 Cbz-L-propargylglycine-OH 
• 598-41-4 H-Gly-NH₂ 
• 917599-63-4 Cbz-L-propargylglycine-OMe 
• 101925-55-7 (S)-propargylglycine methyl ester 
• 23235-01-0 (2S)-2-amino-4-pentynoic acid 

Relevant articles and documents

Cu-catalyzed formation of triazole-linked glycoamino acids and application in chemoenzymatic peptide synthesis

Novel stable triazole-linked glycoamino acids have been prepared, with the heterocyclic moiety being established by efficient Cumediated cycloaddition between the corresponding azido and acetylene moieties. Selected reactions were scaled up and successful

Chemoenzymatic synthesis of triazole-linked glycopeptides

Triazole-linked glycopeptides are prepared by C-terminal elongation of glycoamino acids with proteinogenic amino acids following a chemical or enzymatic coupling protocol. Two orthogonal routes for a chemoenzymatic strategy were explored, involving a click-reaction before amide bond formation or in reverse order. It was found that enzymatic peptide coupling under the influence of alcalase proceeds cleanly and in high yields, while the resulting dipeptides can be efficiently clicked to acetylene- or azide-containing sugars. Georg Thieme Verlag Stuttgart.