91774-53-7

Basic information

• Product Name: 4-Hydroxy-4-Methyl-Hexahydro-1H-azepine hydrochloride
• Synonyms: 4-Hydroxy-4-Methyl-Hexahydro-1H-azepine hydrochloride;4-Methyl-azepan-4-ol hydrochloride;1H-Azepin-4-Ol, Hexahydro-4-Methyl Hydrochloride
• CAS NO: 91774-53-7
• Molecular Formula: C₇H₁₅NO*ClH
• Molecular Weight: 165.66104
• Mol File: 91774-53-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Hydroxy-4-Methyl-Hexahydro-1H-azepine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxy-4-Methyl-Hexahydro-1H-azepine hydrochloride(91774-53-7)
• EPA Substance Registry System: 4-Hydroxy-4-Methyl-Hexahydro-1H-azepine hydrochloride(91774-53-7)

Safety Data

• Hazardous Substances Data: 91774-53-7(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-4-Methyl-Hexahydro-1H-azepine hydrochloride is a chemical compound with the molecular formula C7H15NO. It is often used as a pharmaceutical intermediate and in the synthesis of various organic compounds. 4-Hydroxy-4-Methyl-Hexahydro-1H-azepine hydrochloride is a hydrochloride salt of 4-hydroxy-4-methyl-hexahydro-1H-azepine, a cyclic amine that contains a six-membered ring. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various medications. Additionally, it may also have applications in other industries such as the production of agrochemicals and dyes. This chemical is known for its high reactivity and can be hazardous if not handled properly.

Upstream product

• 878631-04-0 1,1-dimethylethyl 4-hydroxy-4-methylhexahydro-1H-azepine-1-carboxylate 

Downstream Products

• 1354792-13-4 (3-(4-((4-hydroxy-4-methylazepan-1-yl)methyl)phenoxy)azetidin-1-yl)(5-phenyl-1,3,4-oxadiazol-2-yl)methanone 
• 1354792-16-7 (3-(4-((4-hydroxy-4-methylazepan-1-yl)methyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone 
• 878631-05-1 2-[(4-hydroxy-4-methylhexahydro-1H-azepin-1-yl)sulfonyl]benzonitrile 

Relevant articles and documents

NOVEL COMPOUNDS

This invention relates to novel compounds useful in the treatment of diseases associated with TRPV4 channel receptor. More specifically, this invention relates to certain substituted amino -azepines, according to Formula (I). Specifically, the invention is directed to compounds according to Formula (I), wherein: R1 is optionally substituted C3-7cycloalkyl, optionally substituted C3-7cycloalkenyl, optionally substituted Het-C3-7alkyl, optionally substituted Het-C3-7-alkenyl, optionally substituted aryl, optionally substituted heterocycloalkyl, optionally substituted heteroaryl, or optionally substituted indenyl; R2 is H, optionally substituted C1-6alkyl, C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, or Het-C0-6alkyl; each R3 is independently H, optionally substituted C1-8alkyl, optionally substituted C2-8alkenyl, optionally substituted C2-8alkynyl, Het-C1-6 alkyl, optionally substituted C3-6cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted aryl, or optionally substituted heteroaryl, or optionally substituted C1-C6 alkoxy; R4 is H, or optionally substituted C1-C4 alkyl; R5 is H, optionally substituted C1-8alkyl, optionally substituted C2-8alkenyl, optionally substituted C2-8alkynyl, optionally substituted C3-6cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted aryl, or optionally substituted heteroaryl; R6 is H or C1-6alkyl; and X is SO2, CO, CH2, or CONH, and pharmaceutically acceptable salts, hydrates, solvates and pro-drugs thereof.