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6-AMINO-4-CHLORO-3-HYDROXY (1H)INDAZOLE, also known as 4-Chloro-3-hydroxy-6-aminindazole, is a chemical compound with the molecular formula C8H7ClN2O. It is an indazole derivative featuring a chlorine atom at the 4th position and a hydroxyl group at the 3rd position. 6-AMINO-4-CHLORO-3-HYDROXY (1H)INDAZOLE has garnered interest due to its potential as an inhibitor of the enzyme poly (ADP-ribose) polymerase (PARP), which plays a significant role in DNA repair mechanisms.

91775-38-1

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91775-38-1 Usage

Uses

Used in Pharmaceutical Industry:
6-AMINO-4-CHLORO-3-HYDROXY (1H)INDAZOLE is used as an anticancer agent for its potential to inhibit the enzyme PARP. By doing so, it prevents the repair of DNA damage in cancer cells, leading to the selective destruction of these cells. This makes it a promising candidate for the development of targeted cancer therapies.
Used in Biochemical Research:
In the field of biochemical research, 6-AMINO-4-CHLORO-3-HYDROXY (1H)INDAZOLE serves as a valuable tool for studying the role of PARP in various biological processes. Its ability to inhibit PARP activity allows researchers to investigate the enzyme's function and its implications in disease mechanisms, particularly in cancer.
Used in Drug Development:
6-AMINO-4-CHLORO-3-HYDROXY (1H)INDAZOLE is utilized in drug development efforts to create novel therapeutics for the treatment of cancer. Its potential as a PARP inhibitor makes it a key component in the design and synthesis of new drugs aimed at improving patient outcomes and overcoming resistance to existing cancer treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 91775-38-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,7,7 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 91775-38:
(7*9)+(6*1)+(5*7)+(4*7)+(3*5)+(2*3)+(1*8)=161
161 % 10 = 1
So 91775-38-1 is a valid CAS Registry Number.

91775-38-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-amino-4-chloro-1,2-dihydroindazol-3-one

1.2 Other means of identification

Product number -
Other names 6-Amino-4-chloro-3-hydroxy (1H)indazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:91775-38-1 SDS

91775-38-1Upstream product

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