917752-20-6Relevant articles and documents
CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES
-
Page/Page column 73-74, (2010/11/25)
The present invention relates to an asymmetric synthesis useful for preparing compounds useful for the treatment of cardiovascular diseases and for studying the role of motor proteins in cell cycle progression.
Highly diastereoselective asymmetric Mannich reactions of 1,3-dicarbonyls with acyl imines
Ting, Amal,Lou, Sha,Schaus, Scott E.
, p. 2003 - 2006 (2007/10/03)
The cinchona alkaloids catalyze direct asymmetric Mannich reactions of cyclic 1,3-dicarbonyl compounds with acyl imines to afford α-quaternary carbon-bearing reaction products in yields of up to 98%, a diastereomeric excess of 90% or greater, and enantios