917757-15-4 Usage
Uses
Used in Organic Synthesis:
3-Methoxy-4-methylbenzeneboronic acid, 97% is used as a building block in organic synthesis for the creation of complex organic molecules. Its boronic acid functionality allows for versatile reactions, such as Suzuki-Miyaura cross-coupling, which is widely employed for the formation of carbon-carbon bonds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Methoxy-4-methylbenzeneboronic acid, 97% is utilized as an intermediate in the synthesis of various drug molecules. Its unique structure and reactivity enable the development of new compounds with potential therapeutic applications.
Used in Agrochemicals:
3-Methoxy-4-methylbenzeneboronic acid, 97% is employed as a key intermediate in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness and selectivity in controlling pests and unwanted plant growth.
Used in Dye Industry:
In the dye industry, 3-Methoxy-4-methylbenzeneboronic acid, 97% is used as a precursor for the synthesis of various dyes and pigments. Its aromatic and boronic acid structures contribute to the color properties and stability of the resulting dyes, making them suitable for use in textiles, plastics, and other applications.
Check Digit Verification of cas no
The CAS Registry Mumber 917757-15-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,7,7,5 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 917757-15:
(8*9)+(7*1)+(6*7)+(5*7)+(4*5)+(3*7)+(2*1)+(1*5)=204
204 % 10 = 4
So 917757-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H11BO3/c1-6-3-4-7(9(10)11)5-8(6)12-2/h3-5,10-11H,1-2H3
917757-15-4Relevant academic research and scientific papers
Binder, Randall J.,Hatfield, M. Jason,Chi, Liying,Potter, Philip M.
, p. 79 - 89 (2018)
Recently, a series of selective human carboxylesterase inhibitors have been identified based upon the tanshinones, with biologically active molecules containing a 1,2-dione group as part of a naphthoquinone core. Unfortunately, the synthesis of such compounds is complex. Here we describe a novel method for the generation of 1,2-dione containing diterpenoids using a unified approach, by which boronic acids are joined to vinyl bromo-cyclohexene derivatives via Suzuki coupling, followed by electrocyclization and oxidation to the o-phenanthroquinones. This has allowed the construction of a panel of miltirone analogues containing an array of substituents (methyl, isopropyl, fluorine, methoxy) which have been used to develop preliminary SAR with the two human carboxylesterase isoforms. As a consequence, we have synthesized highly potent inhibitors of these enzymes (Ki 15 nM), that maintain the core tanshinone scaffold. Hence, we have developed a facile and reproducible method for the synthesis of abietane analogues that have resulted in a panel of miltirone derivatives that will be useful tool compounds to assess carboxylesterase biology.
