917771-50-7

Basic information

• Product Name: cis-4-fluorocyclohexanol
• Synonyms: cis-4-fluorocyclohexanol
• CAS NO: 917771-50-7
• Molecular Weight: 118.151
• Mol File: 917771-50-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: cis-4-fluorocyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: cis-4-fluorocyclohexanol(917771-50-7)
• EPA Substance Registry System: cis-4-fluorocyclohexanol(917771-50-7)

Safety Data

• Hazardous Substances Data: 917771-50-7(Hazardous Substances Data)

Upstream product

• 405-51-6 4-fluorophenyl acetate 
• 371-41-5 4-Fluorophenol 
• 917771-49-4 (1s,4s)-4-fluorocyclohexyl benzoate 
• 68223-64-3 4-fluorocyclohexan-1-one 

Relevant articles and documents

PROLINE AMIDE COMPOUNDS AND THEIR AZETIDINE ANALOGUES CARRYING A SPECIFICALLY SUBSTITUTED BENZYL RADICAL

The present invention relates to proline amide compounds and their azetidine derivatives of formula I wherein the variables are as defined in the claims and the description. The invention further relates to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT2C receptor, their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT2C receptor, to a method for preventing or treating conditions and disorders which respond to the modulation of the 5-HT2C receptor, and processes for preparing such compounds and compositions.

Synthesis of fluorinated cycloalkyl N-phenylcarbamates and their microbial defluorination/oxygenation by Beauveria bassiana

Earlier investigations showed that cycloalkyl N-phenylcarbamates were hydroxylated by the fungus Beauveria bassiana predominantly in the 4-position relative to the electron-rich substituent. In cases involving fluorinated methylene groups potentially capable of hydroxylation, however, defluorination and formation of a ketone was observed. The formation of the ketone can be explained by primary hydroxylation to forman unstable geminal fluorohydrin, which is subsequently dehydrofluorinated. Wiley-VCH Verlag GmbH & Co. KGaAA, 69451 Weinheim, Germany, 2003.