917833-69-3

Upstream product

• 917833-67-1 tert-butyl (3-phenylpropyl)(1-(trifluoroacetyl)piperidin-4-yl)carbamate 
• 934695-92-8 4-(3-phenyl-propylamino)-piperidine-1-carboxylic acid ethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 58859-46-4 ethyl 4-aminopiperidine-1-carboxylate 

Relevant academic research and scientific papers

NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF

A nitrogen-containing heterocyclic compound represented by the general formula: wherein the dashed line represents a single bond or a double bond; R1, R2, R3, R4 and R5 independently represent a hydrogen atom, halogen atom, a lower alkyl, aryl, lower alkoxy or monocyclic heterocyclic group which may be substituted or the like; R6 represents a lower alkyl, aryl, monocyclic heterocyclic, bicyclic heterocyclic or tricyclic heterocyclic group which may be substituted; X1 represents a lower alkylene group or the like; X2 represents a lower alkylene, lower alkenylene or lower alkynylene group which may be substituted; X3 represents an oxygen atom, sulfur atom, a sulfinyl group, sulfonyl group or the like; Y1 represents a bivalent cyclic group, containing a nitrogen, which may be substituted or the like; and Z1 represents a nitrogen atom, a carbon atom which may be substituted or the like, or a salt thereof. The compound or salt has a potent antibacterial activity and a high safety, and is therefore useful as an excellent antibacterial agent.

Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D2L, D4.2, and 5-HT2A receptors

A series of 1- and 2-naphthamides has been prepared and tested for in vitro binding to D2L, D4.2, and 5-HT2A receptors. Different compounds display selectivity for D4.2 and 5-HT2A receptors versus Ds