91787-23-4Relevant academic research and scientific papers
Highly regioselective ring-opening of aziridines with arenesulfinates on water: A facile access to β-amino/vinyl sulfones
Chawla, Ruchi,Singh, Atul K.,Yadav, Lal Dhar S.
, p. 1720 - 1724 (2013/03/13)
We have developed a LiBr catalyzed efficient synthesis of β-amino sulfones from readily available aziridines and sodium sulfinates in good to excellent yields. The synthetic potential of β-amino sulfones has also been demonstrated by their facile conversion to the corresponding vinyl sulfones. The use of water as reaction media, atom-economy and isolation of products by simple filtration in the case of solid β-amino sulfones are certain green virtues of the synthetic protocol.
Synthesis of Alkenes via Peterson Reaction
Ager, David J.
, p. 183 - 194 (2007/10/02)
The α-phenylthiosilanes (2) have been used to prepare the α-silyl anions (1) by reaction with lithium naphthalenide; subsequent condensation with a carbonyl compound gave the alkene (8) via the Peterson reaction.The α-phenylthiosilanes (2) were prepared from n,n-bis(phenylthio)acetals (4) by reaction with lithium naphthalenide and chlorotrimethylsilane.The n,n-bis(phenylthio)acetals (4) were obtained, in turn, from 1,1-bis(phenylthio)acetals (5) by anion formation with butyl-lithium-N,N,N',N'-tetramethylethylenediamine complex in hexane followed by reaction with an alkyl halide.The Peterson reaction was also used to prepare vinyl sulphides (9) and vinyl sulphones (13).
Reactions of α-Silylsulphones
Ager, David J.
, p. 486 - 488 (2007/10/02)
α-Silylsulphones have been utilised to prepare vinylsulphones via the Peterson reaction and ketones by alkylation, reduction, and sila-Pummerer rearrangement.
