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Aromatic nitro groups and their reactions with chelated ester enolates
Stolz, Daniel,Kazmaier, Uli,Pick, Rigobert
, p. 3341 - 3347 (2008/09/17)
Chelated amino acid ester enolates react with aromatic nitro compounds in a 1,3-addition mode at the nitro group giving amino acids bearing an aryl(hydroxy)amino side chain. Best results were obtained with trifluoroacetyl-protected glycinates. Two equivalents of enolate are necessary for complete conversion, because one equivalent is oxidized during the reaction. Georg Thieme Verlag Stuttgart.
