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CAS

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91800-48-5

8-ethyl-1,3-diazaspiro[4.5]decane-2,4-dione is a complex organic compound with the molecular formula C9H16N2O2. It is a cyclic molecule with a spiro structure, which means it contains two rings that share a common atom. The compound features a 1,3-diaza (two nitrogen atoms) and a spiro[4.5]decane (a decane with a spiro structure) framework. The 8-ethyl group indicates the presence of an ethyl substituent at the 8th position of the molecule. 8-ethyl-1,3-diazaspiro[4.5]decane-2,4-dione is known for its potential applications in pharmaceuticals and as a chiral ligand in asymmetric catalysis. It is synthesized through various chemical reactions and is characterized by its unique structural properties and potential reactivity.

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  • 91800-48-5 Structure

  • Basic information

    1. Product Name: 8-ethyl-1,3-diazaspiro[4.5]decane-2,4-dione
    2. Synonyms:
    3. CAS NO:91800-48-5
    4. Molecular Formula:
    5. Molecular Weight: 196.249
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 91800-48-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 8-ethyl-1,3-diazaspiro[4.5]decane-2,4-dione(CAS DataBase Reference)
    10. NIST Chemistry Reference: 8-ethyl-1,3-diazaspiro[4.5]decane-2,4-dione(91800-48-5)
    11. EPA Substance Registry System: 8-ethyl-1,3-diazaspiro[4.5]decane-2,4-dione(91800-48-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 91800-48-5(Hazardous Substances Data)

91800-48-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 91800-48-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,8,0 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 91800-48:
(7*9)+(6*1)+(5*8)+(4*0)+(3*0)+(2*4)+(1*8)=125
125 % 10 = 5
So 91800-48-5 is a valid CAS Registry Number.

91800-48-5Downstream Products

91800-48-5Relevant articles and documents

Synthesis, characterization and antimicrobial activity of nalidixic acid derivatives with spirohydantoins

Marinov, Marin,Kostova, Iliana,Naydenova, Emilia,Prodanova, Rumyana,Stoyanov, Neyko

, p. 2787 - 2793 (2019/08/01)

This article presents the synthesis of a series of amides, based on the interaction of several 3-aminospirohydantoins with nalidixic acid. The target compounds were characterized by physicochemical parameters, IR, 1H and 13C NMR spectral data. The antimicrobial activity of the products obtained was determined against Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis, Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa and Salmonella abony, the yeasts Candida albicans and Saccharomyces cerevisiae and the molds Penicillium chrysogenum and Aspergillus niger. The relationship between structure and biological activity of the products obtained was discussed. It was found that the most effective compounds are tetralin (5f) and indane (5g) derivatives, which exhibit a pronounced antimicrobial activity against both tested Gram-positive and Gram-negative bacteria.

Synthesis and tumorinhibiting activity of lanthanum(III) complexes with some 1-aminocycloalkancarboxylic acids

Kovachev,Ivanov,Buyukliev,Konstantinov,Karaivanova

, p. 25 - 27 (2007/10/02)

Complexes of La(III) with 1-aminocyclopentane-, -hexane, -heptane and -4-ethylcyclohexanecarboxylic acids were obtained. The compounds were characterized by elemental analyses, IR spectroscopy and conductivity measurements. The following general formula was derived: LaL3Cl3·5 H2O, where L is the corresponding 1-aminocycloalkanecarboxylic acid. The pharmacological studies showed that all complexes manifested higher cytostatic and cytotoxic effects in comparison with lanthanum chloride. Much higher cytotoxic (anti-P388/D1) and cytostatic (anti-L-1210 and antimelanoma-B16) activity was found for the lanthanum complex with 1-aminocyclopentanecarboxylic acid.

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