918132-15-7

Basic information

• Product Name: Boc-Aminooxy-PEG3-bromide
• Synonyms: Boc-Aminooxy-PEG3-bromide;t-Boc-Aminooxy-PEG3-bromide
• CAS NO: 918132-15-7
• Molecular Formula: C13H26BrNO6
• Molecular Weight: 372.25264
• Mol File: 918132-15-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Solubility: Soluble in DMSO, DCM, DMF
• CAS DataBase Reference: Boc-Aminooxy-PEG3-bromide(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Aminooxy-PEG3-bromide(918132-15-7)
• EPA Substance Registry System: Boc-Aminooxy-PEG3-bromide(918132-15-7)

Safety Data

• Hazardous Substances Data: 918132-15-7(Hazardous Substances Data)

Usage

Description

Boc-Aminooxy-PEG3-bromide is a crosslinker that contains a t-Boc-aminooxy group and a bromide (Br). The bromide (Br) serves as an excellent leaving group for nucleophilic substitution reactions, while the t-Boc-aminooxy group can be deprotected under mild acidic conditions. The hydrophilic PEG3 spacer enhances solubility in aqueous media, making it suitable for various applications.

Uses

Used in Bioconjugation:
Boc-Aminooxy-PEG3-bromide is used as a crosslinker for bioconjugation purposes. Its bromide (Br) group facilitates nucleophilic substitution reactions, allowing it to react with various biomolecules, such as proteins, peptides, and antibodies. The t-Boc-aminooxy group can be deprotected under mild acidic conditions, enabling selective conjugation without affecting the integrity of the biomolecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Boc-Aminooxy-PEG3-bromide is used as a component in drug delivery systems. The hydrophilic PEG3 spacer increases the solubility of the drug in aqueous media, improving its bioavailability and therapeutic efficacy. Additionally, the crosslinking ability of the compound allows for the development of targeted drug delivery systems, enhancing the specificity and reducing side effects.
Used in Polymer Science:
Boc-Aminooxy-PEG3-bromide is utilized as a crosslinking agent in polymer science. Its ability to undergo nucleophilic substitution reactions enables the formation of covalent bonds between polymer chains, resulting in the creation of networks or gels with specific properties. The hydrophilic PEG3 spacer also contributes to the overall stability and solubility of the polymeric materials, making them suitable for various applications, such as hydrogels for tissue engineering or responsive materials for environmental sensing.