918142-50-4Relevant academic research and scientific papers
Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs)
Zhao, Zhijian,Wolkenberg, Scott E.,Lu, Meiqing,Munshi, Vandna,Moyer, Gregory,Feng, Meizhen,Carella, Anthony V.,Ecto, Linda T.,Gabryelski, Lori J.,Lai, Ming-Tain,Prasad, Sridar G.,Yan, Youwei,McGaughey, Georgia B.,Miller, Michael D.,Lindsley, Craig W.,Hartman, George D.,Vacca, Joseph P.,Williams, Theresa M.
, p. 554 - 559 (2008)
This Letter describes the design, synthesis, and biological evaluation of novel 3-indole sulfonamides as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) with balanced profiles against common HIV RT mutants K103N and Y181C.
