918149-16-3Relevant academic research and scientific papers
Synthesis of labeled compounds
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Page/Page column 3, (2010/11/25)
The present invention is directed to labeled compounds of the formula Ar-Z1-Q-Z2 where Ar is an aryl group is selected from the group consisting of 1-naphthyl, substituted 1-naphthyl, 2-naphthyl, substituted 2-naphthyl, and phenyl groups with the structure wherein R1, R2, R3, R4 and R5 are each independently selected from the group consisting of hydrogen, a C1-C4 lower alkyl, a halogen, a phenyl, an alkoxy group and an amino group from the group consisting of NH2, NHR and NRR′ where R and R′ are each a C1-C4 lower alkyl, Q is selected from the group consisting of 13CH2, 13CDH and 13CD2, and Z1 is selected from the group consisting of —S—, —S(═O)—, —S(═O)2—, —Se—, ??Se(═O)—, and —Se(═O)2—, Z2 is selected from the group consisting of —Si(R6R7R8), —O(R9), —Se—Ar, —Se(═O)—Ar, —Se(═O)2—Ar, —S—Ar, —S(═O)—Ar, and —S(═O)2—Ar wherein R6, R7 and R8 are each independently selected from the group consisting of a C1-C4 lower alkyl, R9 is a C1-C4 lower alkyl or an R10—Ar group where R10 is a C1-C4 alkylene group.
