91815-76-8Relevant academic research and scientific papers
The Reformatski Reaction of 1-Aryl-2(1H)-pyrimidinones
Katoh, Akira,Omote, Yoshimori,Kashima, Choji
, p. 53 - 55 (2007/10/02)
1-Aryl-2-(1H)-pyrimidinones I reacted with α-haloesters in the presence of zinc to give mainly 3,4-dihydro-4-alkoxycarbonylmethyl-1-aryl-2(1H)-pyrimidinones IV in addition to the minor products of 3,6-dihydro-6-alkoxycarbonylmethyl-1-aryl-2(1H)-pyrimidinones V.Further, 3,4-dihydro derivatives IVa-c were successfully converted into the corresponding exomethylene compounds VIa-c in high yields.
