918151-08-3Relevant academic research and scientific papers
NITROGENOUS N-SUBSTITUTED 4-SPIRO-HETEROCYCLIC 2, 2 -DIMETHYLCHROMANE DERIVATIVES
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Page/Page column 24, (2010/11/29)
A compound having the following general formula:(I) wherein - * represents a chiral center; - R0 is selected from the group comprised of : a carbonyl or thiocarbonyl group, an alkyl group (methylene, ethylene, or methylcarbonyl or methyl-thiocarbonyl grou
New benzopyran-based openers of the mitochondrial ATP-sensitive potassium channel with potent anti-ischemic properties
Breschi, Maria C.,Calderone, Vincenzo,Martelli, Alma,Minutolo, Filippo,Rapposelli, Simona,Testai, Lara,Tonelli, Federica,Balsamo, Aldo
, p. 7600 - 7602 (2007/10/03)
This study was aimed at evaluating, on a limited number of benzopyran compounds, whether the insertion of an electron-rich spirocyclic substituent at the C4 carbon of the benzopyran molecular nucleus may improve the cardioprotective properties against isc
