918159-31-6Relevant academic research and scientific papers
cis-(6RS,13RS)-3,3,10,10-Tetramethyl-6,13-diphenyl-1,8-dioxa-4, 11-diazacyclotetradecane-2,5,9,12-tetraone and two of its precursors
Linden, Anthony,Iliev, Boyan,Heimgartner, Heinz
, p. o339-o343 (2007/10/03)
The title macrocycle, C26H30N2O 6, (VI), was obtained by 'direct amide cyclization' from the linear precursor 3-hydroxy-N-[1-methyl-1-(N-methyl-N-phenylcarbamoyl)ethyl]-2- phenylpropanamide, the N-methylanilide
14-Membered cyclodepsipeptides with alternating β-hydroxy and α-amino acids by cyclodimerization
Iliev, Boyan,Linden, Anthony,Kunz, Roland,Heimgartner, Heinz
, p. 1079 - 1094 (2007/10/03)
The cyclodimerization (twinning) of β-hydroxy acid amides of type 1 under 'direct amide cyclization' (DAC) conditions is described. Although other coupling methods also gave moderate results, best yields were obtained via DAC, reaching 88% for the cyclodi
