918164-33-7Relevant academic research and scientific papers
BENZYLAMINE DERIVATIVES, METHOD FOR OPTICAL RESOLUTION OF BENZYLAMINE DERIVATIVES, PROCESS FOR PRODUCTION OF BENZYLAMINE DERIVATIVES, PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE BENZYLAMINE DERIVATIVES, AND PROCESS FOR PRODUCTION OF (1R, 2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPAN-1-OL
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Page/Page column 15-17, (2008/06/13)
Benzylamine derivatives having structures represented by the general formula (1): (1) a method for the optical resolution of benzylamine derivatives which comprises using optically active mandelic acid as the reagent for optical resolution; and a process for the production of optically active benzylamine derivatives which comprises the optical resolution step of precipitating an optically active (S)-benzylamine derivative represented by the general formula (3) as a salt thereof with (S)-mandelic acid in a solution containing the corresponding benzylamine derivative of the general formula (1) and (S)-mandelic acid: (3) wherein Ar is aryl of 6 to 15 carbon atoms which may be substituted; and *1 represents an asymmetric carbon atom.
