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(R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one (S)-mandelic acid salt is a chemical compound that consists of a (R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one molecule paired with a molecule of (S)-mandelic acid. It is utilized in the field of organic chemistry, particularly for its role as a chiral resolving agent in chromatography.

918164-35-9

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918164-35-9 Usage

Uses

Used in Chromatography:
(R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one (S)-mandelic acid salt is used as a chiral resolving agent for the separation of racemic mixtures into their individual enantiomers. This application is crucial in the study and utilization of the specific properties of each enantiomer, as they can exhibit different biological activities and interactions.
Used in Organic Chemistry:
In the field of organic chemistry, (R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one (S)-mandelic acid salt is used as a chiral auxiliary, assisting in the resolution of racemic mixtures. The (S)-mandelic acid salt component of the compound aids in this process, while the (R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one component provides the necessary chiral center for the resolving agent to function effectively.
Used in Pharmaceutical Industry:
(R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one (S)-mandelic acid salt may also find applications in the pharmaceutical industry, where the separation and analysis of chiral molecules are essential for the development of drugs with specific therapeutic effects and reduced side effects. (R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one (S)-mandelic acid salt's ability to resolve enantiomers can contribute to the discovery and optimization of new pharmaceutical agents.
Used in Research and Development:
In research and development, (R)-2-benzylamino-1-(4-hydroxyphenyl)propane-1-one (S)-mandelic acid salt can be employed to study the effects of different enantiomers on biological systems. This knowledge can be applied to the design of more effective and safer drugs, as well as to understand the mechanisms of action of existing medications.

Check Digit Verification of cas no

The CAS Registry Mumber 918164-35-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,1,6 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 918164-35:
(8*9)+(7*1)+(6*8)+(5*1)+(4*6)+(3*4)+(2*3)+(1*5)=179
179 % 10 = 9
So 918164-35-9 is a valid CAS Registry Number.

918164-35-9Relevant academic research and scientific papers

BENZYLAMINE DERIVATIVES, METHOD FOR OPTICAL RESOLUTION OF BENZYLAMINE DERIVATIVES, PROCESS FOR PRODUCTION OF BENZYLAMINE DERIVATIVES, PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE BENZYLAMINE DERIVATIVES, AND PROCESS FOR PRODUCTION OF (1R, 2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPAN-1-OL

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Page/Page column 15-17, (2008/06/13)

Benzylamine derivatives having structures represented by the general formula (1): (1) a method for the optical resolution of benzylamine derivatives which comprises using optically active mandelic acid as the reagent for optical resolution; and a process for the production of optically active benzylamine derivatives which comprises the optical resolution step of precipitating an optically active (S)-benzylamine derivative represented by the general formula (3) as a salt thereof with (S)-mandelic acid in a solution containing the corresponding benzylamine derivative of the general formula (1) and (S)-mandelic acid: (3) wherein Ar is aryl of 6 to 15 carbon atoms which may be substituted; and *1 represents an asymmetric carbon atom.

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