918303-91-0Relevant academic research and scientific papers
Selective Ruthenium-Catalyzed Reductive Alkoxylation and Amination of Cyclic Imides
Cabrero-Antonino, Jose R.,Sorribes, Ivn,Junge, Kathrin,Beller, Matthias
supporting information, p. 387 - 391 (2016/01/25)
Reported herein, for the first time, is the selective ruthenium-catalyzed reductive alkoxylation and amination of phthalimides/succinimides. Notably, this novel methodology avoids hydrogenation of the aromatic ring and allows methoxylation of substituted imides with good to excellent selectivity for one of the carbonyl groups. The reported method opens the door to the development of new processes for the selective synthesis of various functionalized N-heterocyclic compounds. As an example, intramolecular reductive couplings to afford tricyclic compounds are presented for the first time.
The crucial role of the nitrogen substituent in the desymmetrisation of cyclic meso-imides using B-Me and B-OMe oxazaborolidine catalysts
Barker, Mike D.,Dixon, Rachel A.,Jones, Simon,Marsh, Barrie J.
, p. 11663 - 11669 (2007/10/03)
Various cyclic meso-imides have been desymmetrised via enantioselective reduction using two chiral oxazaborolidine catalysts derived from (1R,2S)-cis-1-amino-indan-2-ol followed by the reduction of the hydroxylactam product to give the γ-lactam. The enant
Synthesis of lactams by regioselective reduction of cyclic dicarboximides
Milewska, Maria J.,Bytner, Tomasz,Polonski, Tadeusz
, p. 1485 - 1488 (2007/10/03)
Lactams can be obtained by the monothionation of imides with Lawesson's reagent followed by the desulfurization of resulted monothioimides with Raney nickel.
