918327-95-4

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 918328-47-9 1-(2-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol 
• 41052-75-9 o-chlorophenylhydrazine hydrochloride 

Downstream Products

• 1033575-73-3 1-(2-chlorophenyl)-5-(3-methanesulfonylphenylethynyl)-3-trifluoromethyl-1H-pyrazole 
• 1033575-72-2 3-[2-(2-chlorophenyl)-5-trifluoromethyl-2H-pyrazol-3-ylethynyl]benzenesulfonamide 

Relevant academic research and scientific papers

LXR AND FXR MODULATORS

Compounds of the invention are disclosed, such as compounds of formulae LX - LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R00, R200, R400, R500, J11, J21, G1, G21, and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.