918340-50-8

Basic information

• Product Name: 1-CHLOROPYRROLO[1,2-C]PYRIMIDINE
• Synonyms: 1-CHLOROPYRROLO[1,2-C]PYRIMIDINE;1-CHLOROH-PYRROLO[1,2-F]PYRIMIDINE
• CAS NO: 918340-50-8
• Molecular Formula: C₇H₅ClN₂
• Molecular Weight: 152.58
• Mol File: 918340-50-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.35g/cm³
• Refractive Index: 1.653
• CAS DataBase Reference: 1-CHLOROPYRROLO[1,2-C]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLOROPYRROLO[1,2-C]PYRIMIDINE(918340-50-8)
• EPA Substance Registry System: 1-CHLOROPYRROLO[1,2-C]PYRIMIDINE(918340-50-8)

Safety Data

• Hazardous Substances Data: 918340-50-8(Hazardous Substances Data)

Usage

Description

1-CHLOROPYRROLO[1,2-C]PYRIMIDINE is a heterocyclic compound that features a chloro group attached to a pyrrolo[1,2-c]pyrimidine ring system. This unique structure endows it with distinctive chemical properties and reactivity, making it a valuable molecule for organic synthesis and drug discovery.

Uses

Used in Pharmaceutical Industry:
1-CHLOROPYRROLO[1,2-C]PYRIMIDINE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its potential applications include the development of new drugs that can address unmet medical needs or improve upon existing treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 1-CHLOROPYRROLO[1,2-C]PYRIMIDINE serves as a chemical intermediate, contributing to the creation of innovative crop protection products. This can lead to more effective and sustainable agricultural solutions.
Used in Organic Synthesis:
1-CHLOROPYRROLO[1,2-C]PYRIMIDINE is utilized as a building block in the synthesis of other heterocyclic compounds. These compounds may possess a range of biological activities, further expanding the scope of its applications in various fields.
Used in Drug Discovery:
Due to its unique structure and reactivity, 1-CHLOROPYRROLO[1,2-C]PYRIMIDINE plays a significant role in drug discovery efforts. It can be instrumental in the design and development of novel therapeutic agents with improved efficacy and selectivity.

InChI:InChI=1/C7H5ClN2/c8-7-9-4-3-6-2-1-5-10(6)7/h1-5H

Upstream product

• 811450-47-2 2-chloro-4-prop-1-yn-1-ylpyrimidine 

Downstream Products

• 918340-61-1 2-chloro-5-(pyrrolo[1,2-c]pyrimidin-1-ylamino)-phenol 

Relevant articles and documents

NEW CRTH2 ANTAGONISTS

The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.

COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER

The present invention relates to compounds according to the formula I: Where Ra is H or an optionally OH-substituted C1-C3 alkyl; R1 is OR1, an optionally substituted C4-12 carbocyclic group which may be saturated or unsaturated (including aromatic) or an optionally substituted heterocyclic group; R1 is an optionally substituted C1-C14 hydrocarbyl group or an optionally substituted heterocyclic group;; R2 , R3 and R4 are each independently H, an optionally substituted C1-C4 alkyl group (preferably CH3, CH2CH3 or CF3), halogen (preferably F, Cl, Br), OR, CN, NO2, a C1-C6 thioether, a C1-C6 thioester group, an optionally substituted CO2R group, an optionally substituted COR group or an optionally substituted OCOR group (preferably R4 is H); R is H or an optionally substituted C1-C6 alkyl group; RHET is an optionally substituted heterocyclic group; and pharmaceutically acceptable salts, solvates or polymorphs thereof.