91854-80-7

Upstream product

• 89-93-0 ortho-methylbenzylamine 
• 529-20-4 2-methylphenyl aldehyde 
• 1431623-81-2 C₁₂H₁₇NOS 

Downstream Products

• 189180-11-8 diethyl (2-methylphenyl)(amino)methylphosphonate 
• 1246495-50-0 diethyl {[(2-hydroxy-3-(4-phenoxy)propyl)amino](o-tolyl)methyl}phosphonate 
• 1246495-55-5 diethyl {[(2-hydroxy-3-(isopropoxy)propyl)amino](o-tolyl)methyl}phosphonate 
• 529-19-1 2-Methylbenzonitrile 
• 872595-04-5 (+)-(R,R)-1,2-bis(2-methylphenyl)ethylene-1,2-diamine 
• 1005173-83-0 (-)-(S,S)-1,2-bis(2-methylphenyl)ethylene-1,2-diamine 

Relevant academic research and scientific papers

Enantioselective Reductive Coupling of Imines Templated by Chiral Diboron

We herein report a general, practical, and highly efficient method for asymmetric synthesis of a wide range of chiral vicinal diamines via reductive coupling of imines templated by chiral diboron. The protocol features high enantioselectivity and stereospecificity, mild reaction conditions, simple operating procedures, use of readily available starting materials, and a broad substrate scope. The method signifies the generality of diboron-enabled [3,3]-sigmatropic rearrangement.

Boron-nitrogen derivative used for organic electroluminescence

The invention provides a boron-nitrogen derivative used for organic electroluminescence. The boron-nitrogen derivative is characterized by having a structure as shown in a general formula (I) which is described in the specification. In the general formula (I), A is C or N; and n and m are any number selected from the group consisting of 0, 1, 2 and 3. Furthermore, the invention also provides an organic electroluminescent blue-light emitting host material, an electron injection material, an electronic transmission material and a device containing the above-mentioned boron-nitrogen derivative. The boron-nitrogen derivative provided by the invention has good solubility and thermal stability, is used as a blue-light emitting host material, and can simultaneously solve the disadvantages of easy crystallization of a small molecule object material and low Tg of a wide energy band host material.

Solvent-and catalyst-free reaction of (aminomethyl)phosphonates with epoxides: Synthesis of novel {[(2-hydroxyethyl)amino]methyl}phosphonates

Uncatalyzed reaction of epoxides with (aminomethyl)phosphonates for the synthesis of novel {[(2-hydroxyethyl)amino]methyl}phosphonates is described. Treatment of (aminomethyl)phosphonates with epoxides without any catalyst and under solvent-free condition

Synthesis of some 2-aminonitroethanes via tin(II)chloride mediated addition reaction of bromonitromethane to imines

In the presence of tin(II)chloride, bromonitromethane reacts with imines derived from aromatic aldehydes and ammonia to yield 2-amino-2-aromatic substituted nitroethane derivatives via an addition reaction in good yields.

Correlation analysis of reactivity in the oxidation of substituted benzylamines by pyridinium hydrobromide perbromide

The oxidation of benzylamine and twenty-seven ortho-, meta- and para-substituted benzylamines by pyridinium hydrobromide perbromide (PHPB), in dimethylsulphoxide (DMSO), leads to the formation of the corresponding aldimines. The reactions are of first order with respect to both PHPB and the amine. The oxidation of deuterated benzylamine exhibited a substantial kinetic isotope effect (kII/kD = 3.20 at 303 K). An addition of pyridinium bromide does not affect the rate. PHPB itself has been postulated as the reactive oxidizing species. The rates of the oxidation of para- and meta-substituted benzylamines were correlated with Taft's and Swain's field and resonance substituent constants. The oxidation of para-substituted benzylamines showed an excellent correlation with Taft's σI and σRBA values; the meta-compounds correlated best with σI and σR0 values. Rates of the ortho-substituted compounds showed a significant correlation with Charton's triparametric equation. Suitable mechanism has been proposed.

Correlation analysis of reactivity in the oxidation of substituted benzylamines by benzyltrimethylammonium tribromide

The oxidation of benzylamine and twenty-seven ortho-, meta- and para-monosubstituted benzylamines by benzyltrimethylammonium tribromide (BTMAB), in dimethylsulphoxide (DMSO), leads to the formation of corresponding aldimines. The reaction is first order with respect to both BTMAB and the amine. The oxidation of deuterated benzylamine exhibited a substantial kinetic isotope effect. Addition of benzyltrimethylammonium bromide does not affect the rate. Tribromide ion has been postulated as the reactive oxidizing species. The rates of the oxidation of para- and meta-substituted benzylamines showed excellent correlation in terms of both Taft's dual substituent-parameter and Charton's triparametric LDR equations, whereas the ortho-substituted compounds exhibited the best correlation with the Charton's tetraparametric LDRS equation. The oxidation of para-substituted benzylamines is more susceptible to the delocalization effect than is the oxidation of ortho- and meta-substituted compounds, which display a greater dependence on the field effect. The low positive value of the η suggests the presence of an electron-deficient centre in the rate-determining transition state with less charge separation. A suitable mechanism has been proposed.