918659-10-6

Basic information

• Product Name: Dehydro Azelnidipine
• Synonyms: Dehydro Azelnidipine
• CAS NO: 918659-10-6
• Molecular Formula: C₃₃H₃₂N₄O₆
• Molecular Weight: 580.63038
• Mol File: 918659-10-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Hested)
• CAS DataBase Reference: Dehydro Azelnidipine(CAS DataBase Reference)
• NIST Chemistry Reference: Dehydro Azelnidipine(918659-10-6)
• EPA Substance Registry System: Dehydro Azelnidipine(918659-10-6)

Safety Data

• Hazardous Substances Data: 918659-10-6(Hazardous Substances Data)

Usage

Uses

Dehydro Azelnidipine is a derivative of Azelnidipine (A808500), a calcium channel blocker that is used as an antihypertensive treatment. Azelnidipine also has anti-atherosclerotic effects.

Upstream product

• 123524-52-7 azelnidipine 

Relevant articles and documents

Identification and synthesis of impurities formed during preparation of azelnidipine

Azelnidipine (1), dihydropyridine-based calcium antagonists (DHPs) are one of the widely used drugs for treatment of hypertension. During the laboratory optimization and later during its bulk synthesis the formation of various impurities was observed. The impurities formed were monitored and their structures were tentatively assigned on the basis of their fragmentation patterns in LC-MS. Most of the impurities were synthesized and their assigned constitutions confirmed by co-injection in HPLC. We describe herein the formation, synthesis and characterization of these impurities. Our study will be of immense help to others to obtain chemically high pure azelnidipine.