918665-35-7Relevant academic research and scientific papers
Radical 4-exo cyclizations onto O-alkyloxime acceptors: Towards the synthesis of penicillin-containing antibiotics
Scanlan, Eoin M.,Walton, John C.
, p. 2133 - 2143 (2006)
The 4-exo cyclizations of two types of carbamoyl radicals onto O-alkyloxime acceptor groups were studied as potential routes to 3-amino-substituted azetidinones and hence to penicillins. A general synthetic route to 'benzaldehyde oxime oxalate amides' (=2
Chiral aminal templates: Diastereoselective addition to hydrazones; an asymmetric synthesis of α-amino aldehydes
Alexakis,Lensen,Tranchier,Mangeney,Feneau-Dupont,Declercq
, p. 1038 - 1050 (2007/10/02)
The monohydrazone of glyoxal may be derivatized into a chiral aminal with diamine 7. The resulting chiral reagent 13 reacts with complete diastereocontrol with organolithium reagents in THF. This sterically controlled reaction may be altered to chelation
