918803-85-7Relevant academic research and scientific papers
Introduction of the acetate unit to the 2-pyridinone ring system and its application to the synthesis of (20S)-camptothecin DE ring system
Hiroya, Kou,Kawamoto, Kei,Sakamoto, Takao
, p. 2636 - 2640 (2008/09/16)
The DE ring system of (20S)-camptothecin had been prepared from commercially available nicotinic acid in six steps utilizing the nucleophilic addition reaction of the silyl ketene acetal to the pyridinone ring as a key step. Georg Thieme Verlag Stuttgart.
