918879-75-1

Upstream product

• 938182-54-8 ethyl 5-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate 
• 2210-74-4 2-(2-methoxy-phenoxymethyl)-oxirane 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 35322-20-4 ethyl 3-(4-methoxybenzoyl)pyruvate 

Downstream Products

• 1051971-06-2 1-(2'-hydroxy-3'-(2'-methoxyphenoxy)propyl)-3-(4'-methoxyphenyl)-1H-pyrazole-5-carbohydrazide 

Relevant academic research and scientific papers

Microwave-assisted rapid and straightforward synthesis of novel 6-(aroxymethyl)-2-aryl-6,7-dihydropyrazolo[5,1-c][1,4]oxazin-4-one derivatives

A series of novel 6-(aroxymethyl)-2-aryl-6,7-dihydropyrazolo[5,1-c][1,4] oxazin-4-one derivatives was synthesized from ethyl 3-aryl-1H-pyrazole-5- carboxylate and 2-aryloxymethylepoxide by a microwave-assisted, one-step method in good yields. The microwave-assisted reaction of ethyl 3-aryl-1H-pyrazole-5- carboxylate and 2-aryloxymethylepoxide proceeds with higher regioselectivity and is more economical and environmentally friendly in contrast to the normal intramolecular esterification route. A tandem mechanism of the reaction was proposed. Copyright Taylor & Francis Group, LLC.

Design, synthesis, and preliminary biological evaluation of novel ethyl 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carboxyla te

We synthesized a series of novel small molecules, ethyl 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carboxyla te derivatives 3a-3o, by the reaction of ethyl 3-aryl-1H-pyrazole-5-carboxylate with 2-aryloxymethylepoxide in the presence of potassium c