91891-62-2Relevant academic research and scientific papers
One-pot synthesis of aminoenone via direct reaction of the chloroalkyl enone with NaN3: Rapid access to polycyclic alkaloids
Zhao, Yu-Ming,Gu, Peiming,Tu, Yong-Qiang,Zhang, Hai-Jun,Zhang, Qing-Wei,Fan, Chun-An
supporting information; experimental part, p. 5289 - 5295 (2010/10/19)
(Figure presented) A new one-pot procedure for the preparation of aminoenone from chloroalkyl enone and sodium azide was demonstrated. The structure of the presumed triazoline intermediate in this process was confirmed by X-ray analysis for the first time. As the application of this methodology, the synthesis of polycyclic alkaloid hexahydroapoerysopine (1a) was achieved through an efficient synthetic route.
Thermal rearrangements of α-(ω-azidoalkyl) enones
Molander, Gary A.,Bibeau, Christopher T.
, p. 5385 - 5388 (2007/10/03)
The thermal rearrangement of α-(ω-azidoalkyl) enones has been investigated. A variety of these substrates were synthesized and subjected to thermal rearrangement to investigate the scope and generality of their transformation to bicyclic lactams.
Intramolecular 1,3-Dipolar Cycloaddition of Alkyl Azide Enones and Rearrangements of the Triazoline Interemediates. Formal Total Synthesis of (+/-)-Desamylperhydrohistrionicotoxin
Sha, Chin-Kang,Ouyang, Sheng-Lian,Hsieh, Der-Yung,Chang, Ruei-Chih,Chang, Shang-Chia
, p. 1490 - 1494 (2007/10/02)
Azido enones 8,18,25,39, and 45, which were prepared by the treatment of the corresponding bromide 7, methanesulfonate 17, chloride 24, bromide 38, and toluenesulfonate 44 with sodium azide, were found to undergo intramolecular 1,3-dipolar cycloaddition r
