918952-57-5Relevant academic research and scientific papers
New synthesis of (±)-isonucleosides
Yoshimura, Yuichi,Asami, Kazuhiro,Matsui, Hiromitsu,Tanaka, Hiromichi,Takahata, Hiroki
, p. 6015 - 6018 (2006)
(Chemical Equation Presented) A novel method for synthesizing isonucleosides, a new class of anti-HIV nucleosides, is described. 2,2-Dimethyl-1,3-dioxan-5-one was converted into a dioxabicyclohexane derivative in six steps. After cleaving the epoxide grou
Design and synthesis of isonucleosides constructed on a 2-Oxa-6-thiabicyclo[3.2.0]heptane Scaffold (1)
Yoshimura, Yuichi,Asami, Kazuhiro,Imamichi, Tomozumi,Okuda, Tomoko,Shiraki, Kimiyasu,Takahata, Hiroki
, p. 4161 - 4171 (2010)
A novel method for the design and synthesis of an isonucleoside containing a 2-oxa-6-thiobicyclo[3.2.0]heptane skeleton is described. 2,2-Dimethyl-1,3- dioxan-5-one 13 was converted into a dioxabicyclohexane derivative in six steps. After cleavage of the
