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91903-82-1

[2-hydroxy-3-(methoxycarbonyl)naphthalen-1-yl]methanesulfonic acid, commonly known as Mesna, is a sulfhydryl donor drug that plays a crucial role in the field of cancer chemotherapy. It is specifically designed to mitigate the urotoxicity and nephrotoxicity associated with the use of oxazaphosphorine anti-cancer drugs, such as ifosfamide and cyclophosphamide. Mesna achieves this by acting as a scavenger for the harmful metabolites produced by these drugs, which can cause bladder irritation and damage to the kidneys. Its ability to bind to and detoxify these metabolites makes it an essential component in the treatment regimen for patients undergoing chemotherapy with oxazaphosphorines.

91903-82-1

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91903-82-1 Usage

Uses

Used in Cancer Chemotherapy:
Mesna is used as a protective agent in cancer chemotherapy to prevent or reduce the urotoxicity and nephrotoxicity caused by oxazaphosphorine anti-cancer drugs. It functions by scavenging the metabolites of these drugs, which are responsible for bladder irritation and kidney damage. By binding to and detoxifying these harmful metabolites, Mesna helps to protect the bladder and kidneys from potential harm, thereby improving the safety and tolerability of oxazaphosphorines in cancer treatment.
Used in Drug Administration:
Mesna is administered orally or intravenously as part of the treatment regimen for patients undergoing chemotherapy with oxazaphosphorines. Its effectiveness in mitigating the toxic effects of these drugs on the urinary system has made it a standard component in cancer chemotherapy, contributing to the overall well-being and quality of life of patients receiving this type of treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 91903-82-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,9,0 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 91903-82:
(7*9)+(6*1)+(5*9)+(4*0)+(3*3)+(2*8)+(1*2)=141
141 % 10 = 1
So 91903-82-1 is a valid CAS Registry Number.

91903-82-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-hydroxy-3-methoxycarbonylnaphthalen-1-yl)methanesulfonic acid

1.2 Other means of identification

Product number -
Other names [2-hydroxy-3-(methoxycarbonyl)naphthalen-1-yl]methanesulfonic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:91903-82-1 SDS

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