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Usage

Uses

Used in Pharmaceutical Industry:
[(2,2-diethoxyethyl)sulfanyl]methylbenzene is used as a building block for the synthesis of various pharmaceuticals due to its organosulfur content and reactive functional groups. Its ability to be incorporated into the molecular structures of drugs makes it a versatile component in the development of new medications.
Used in Pesticide Industry:
In the pesticide industry, [(2,2-diethoxyethyl)sulfanyl]methylbenzene is utilized as a key component in the creation of different pesticides. Its chemical properties allow it to be tailored to target specific pests while minimizing environmental impact.
Used in Materials Science:
The sulfur-containing moiety of [(2,2-diethoxyethyl)sulfanyl]methylbenzene also makes it a candidate for applications in materials science. It can be used in the development of novel materials with specific properties, such as those with enhanced thermal or chemical stability, depending on the requirements of various applications.
Used in Organic Synthesis:
As a fundamental component in organic synthesis, [(2,2-diethoxyethyl)sulfanyl]methylbenzene is used as an intermediate for the production of a wide range of fine chemicals. Its unique structure allows for further functionalization and the creation of more complex molecules for various applications across different industries.

Upstream product

• 621-62-5 chloroacetaldehyde diethyl acetal 
• 100-53-8 phenylmethanethiol 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Downstream Products

• 79428-40-3 [2-Benzylsulfanyl-1-(3-phenyl-thioureido)-ethyl]-phosphonic acid diphenyl ester 
• 639076-76-9 (2S,1R,2S)-(-)-{1-[1-benzylsulfanyl-2-(naphthalen-2-yl)ethyl]pentyl}[2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-85-0 (2S,1R,2S)-(-)-[1-(1-benzylsulfanyl-2-phenylethyl)heptyl][2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-74-7 (2S,1R,2S)-(-)-{1-[1-benzylsulfanyl-2-(o-tolyl)ethyl]pentyl}[2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-82-7 (2S,1R,2S)-(-)-[1-benzylsulfanyl-3-(phenylpropyl)pentyl][2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-79-2 (2S,1R,2S)-(-)-[1-(1-benzylsulfanyl-2-phenylethyl)pentyl][2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-70-3 (2S,2S)-(-)-[2-benzylsulfanyl-3-(4-tert-butylphenyl)propylidene][2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-58-7 (2S,2S)-(-)-[2-benzylsulfanyl-3-(naphthalen-2-yl)propylidene][2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-73-6 (2S,1R,2S)-(-)-(2-benzylsulfanyl-1-butyl-4-methylpentyl)[2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639077-10-4 methyl (2S,1R)-(+)-[1-(1-benzylsulfanyl-2-phenylethyl)heptyl]carbamate 
• 639076-55-4 (2S,2S)-(2-benzylsulfanyl-3-o-tolylpropylidene)[2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-71-4 (2S,1R,2S)-[1-(1-benzylsulfanyl-2-methylpropyl)pentyl][2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-88-3 (2S,1R,2S)-(-)-[2-benzylsulfanyl-1-methyl-3-phenylpropyl][2-(methoxymethyl)pyrrolidin-1-yl]amine 
• 639076-64-5 (2S,2S)-(2-benzylsulfanyl-4-phenylbutylidene)[2-(methoxymethyl)pyrrolidin-1-yl]amine 

Relevant academic research and scientific papers

Synthesis and properties of alkylthioethanals

A method, allowing alkylthioethanals to be synthesized in 80-93% yields, has been developed. It comprises the hydrolysis of bis-1,1-alkoxy-2- alkylthioethanes using two-phase system water - organic solvent. The method is applicable for both common aldehyd

A Flexible Asymmetric Synthesis of anti-1,2-Sulfanyl Amines

An efficient and flexible asymmetric synthesis of various protected anti-1,2-sulfanyl amines bearing two adjacent stereogenic centres is described. Key steps are the diastereoselective α-alkylation of α-sulfanylated acetaldehyde-SAMP-hydrazones with various electrophiles and subsequent nucleophilic 1,2-addition of organocerium reagents to the hydrazone CN double bond. The resulting hydrazines were converted into the title compounds with excellent diastereomeric and enantiomeric excesses (de and ee values ≥ 96%) by reductive N,N bond cleavage to remove the chiral auxiliaries and protection of the amino functions. The relative and absolute configurations were determined by NOE experiments and X-ray structure analysis. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

Building units for N-backbone cyclic peptides. Part 4. Synthesis of protected Nα-functionalized alkyl amino acids by reductive alkylation of natural amino acids

A new method for the synthesis of protected Nα-(ω-Y-alkyl) amino acids (Y is a thio, amino or carboxy group) and related compounds by reductive alkylation of natural amino acids is reported. These new amino acids serve as building units for the synthesis of backbone-cyclic peptides. They are orthogonally protected at the α-amino position by butoxycarbonyl (Boc) or 9-fluorenylmethoxycarbonyl (Fmoc), using trimethylsilyl temporary protection, to allow for their incorporation into peptides by solid phase peptide synthesis.

Enantioselective Synthesis of 2-Sulfenylated Aldehydes: Alkylation of Sulfenylated Acetaldehyde SAMP-Hydrazones

A practical and efficient enantioselective synthesis of 2-sulfenylated aldehydes (S)-6 is described, based on the α-alkylation of sulfenylated acetaldehyde SAMP hydrazones (S)-4, easily prepared from bromoacetaldehyde diethylacetal 1, thiols and (S)-1-amino-2-methoxymethyl-pyrrolidine (SAMP).A chemoselective oxidative cleavage of the intermediate SAMP hydrazones (S,S)-5 with ozone gives rise to the title compounds (S)-6 in good overall yields and high enantiomeric excess of up to 97percent.