919092-54-9Relevant academic research and scientific papers
Structural requirement of chalcones for the inhibitory activity of interleukin-5
Yang, Hyun-Mo,Shin, Hye-Rim,Cho, Soo-Hyun,Bang, Seong-Cheol,Song, Gyu-Yong,Ju, Jung-Hun,Kim, Mi-Kyeong,Lee, Seung-Ho,Ryu, Jae-Chun,Kim, Youngsoo,Jung, Sang-Hun
, p. 104 - 111 (2007)
Novel chalcones were found as potent inhibitors of interleukin (IL)-5. 1-(2-Benzyloxy-6-hydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one (2b, 78.8% inhibition at 50 μM, IC50 = 25.3 μM) was initially identified as a potent inhibitor of IL-5. Th
