91923-30-7

Basic information

• Product Name: Cyclohexanecarbothioic acid, O-methyl ester
• CAS NO: 91923-30-7
• Molecular Formula: C8H14OS
• Molecular Weight: 158.265
• Mol File: 91923-30-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarbothioic acid, O-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarbothioic acid, O-methyl ester(91923-30-7)
• EPA Substance Registry System: Cyclohexanecarbothioic acid, O-methyl ester(91923-30-7)

Safety Data

• Hazardous Substances Data: 91923-30-7(Hazardous Substances Data)

Upstream product

• 2812-72-8 methyl chlorothioformate 
• 4630-82-4 methyl cyclohexylcarboxylate 

Downstream Products

• 63822-79-7 O-(2-(2-hydroxyethoxy)ethyl) cyclohexanecarbothioate 
• 1415241-07-4 cyclohexanecarboselenothioic acid Se-2-(trimethylsilyl)ethyl ester 
• 1415241-23-4 cyclohexanecarboselenothioic acid Se-methyl ester 
• 1415241-22-3 tetrabutylammonium cyclohexanecarboselenothioate 

Relevant articles and documents

Base-Catalyzed Transesterification of Thionoesters

Here we report a convenient synthesis of thionoesters by base-catalyzed transesterification. Benzyl and alkyl thionobenzoates and thionoheterobenzoates were efficiently prepared using various alcohols catalyzed by the corresponding sodium alkoxide. This methodology features a broad substrate scope, good to excellent yields, short reaction times, while simultaneously driving the reaction toward completion through the removal of the methanol byproduct. We also report the conversion of a small collection of thionobenzoates into the corresponding α,α-difluorobenzyl ethers to demonstrate the conversion of alcohols into difluorobenzyl or difluoroheterobenzyl ethers, a process that could prove useful for lead optimization in medicinal chemistry.

Difluorination of Esters. Preparation of α,α-Difluoro Ethers

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