919357-46-3

Basic information

• Product Name: benzyl 3,5-difluoro-4-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]phenylcarbamate
• Synonyms: benzyl 3,5-difluoro-4-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]phenylcarbamate
• CAS NO: 919357-46-3
• Molecular Weight: 402.321
• Mol File: 919357-46-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl 3,5-difluoro-4-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]phenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 3,5-difluoro-4-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]phenylcarbamate(919357-46-3)
• EPA Substance Registry System: benzyl 3,5-difluoro-4-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]phenylcarbamate(919357-46-3)

Safety Data

• Hazardous Substances Data: 919357-46-3(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 

Downstream Products

• 919357-49-6 tert-butyl ((5S)-3-{3,5-difluoro-4-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl)methylcarbamate 

Relevant articles and documents

A distal methyl substituent attenuates mitochondrial protein synthesis inhibition in oxazolidinone antibacterials

Oxazolidinone analogs bearing substituted piperidine or azetidine C-rings are described. Analogs with a methyl group at the 3-position of the azetidine ring or the 4-position of the piperidine ring exhibited reduced mitochondrial protein synthesis inhibition while retaining good antibacterial potency.