91945-49-2

Usage

Type

Ester derivative

Derivative of

3-Isoxazolepropanoic acid

Common uses

Organic synthesis

Potential biological activities

Yes

Applications

Medicinal chemistry, agrochemicals, material science

Properties

Interesting properties, potential pharmacological activities

Building block in synthesis of

Pharmaceuticals, organic compounds

Upstream product

• 80073-32-1 5-methyl-3-isoxazolepropanoic acid 

Relevant academic research and scientific papers

Di-heterocyclic compounds and their use as antiviral agents

Compounds of the formulas: STR1 wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.

Isoxazoles as antiviral agents

Compounds of the formulas: STR1 wherein R is alkyl, X is O or CH2, n is an integer from 4 to 8, and Ar is phenyl or substituted phenyl are useful as antiviral agents especially against picornaviruses.