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Duloxetine-d7 is a labeled form of Duloxetine, an antidepressant that functions as a dual serotonin and norepinephrine reuptake inhibitor (SNRI). It is characterized by its ability to inhibit the reuptake of both serotonin and norepinephrine, leading to increased levels of these neurotransmitters in the synaptic cleft. This results in improved mood, reduced anxiety, and enhanced cognitive function. The current lot of Duloxetine-d7 is 97% purity with no presence of d0, d1, or d2 isotopes.

919514-01-5

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919514-01-5 Usage

Uses

Used in Pharmaceutical Industry:
Duloxetine-d7 is used as a research and development tool for the pharmaceutical industry. It aids in the investigation of the pharmacological properties, metabolism, and mechanism of action of Duloxetine. This labeled compound is particularly useful for studying the drug's interaction with its target receptors and enzymes, as well as its distribution, absorption, and excretion in the body.
Used in Clinical Research:
Duloxetine-d7 is employed as a diagnostic and monitoring tool in clinical research. It helps in assessing the efficacy and safety of Duloxetine as a treatment for various conditions, such as major depressive disorder, generalized anxiety disorder, and stress urinary incontinence. The labeled compound allows for the tracking of drug levels in patients' blood and tissues, providing valuable information on dosage optimization and potential side effects.
Used in Stress Urinary Incontinence Treatment:
Duloxetine-d7 is used as a therapeutic agent for the treatment of stress urinary incontinence. As a dual serotonin and norepinephrine reuptake inhibitor, it helps to increase the levels of these neurotransmitters in the brain, which in turn enhances the function of the pelvic floor muscles and improves bladder control. This results in a reduction of involuntary urine leakage and an overall improvement in the quality of life for patients suffering from this condition.
Used in Antidepressant Therapy:
Duloxetine-d7 is utilized as an antidepressant medication for the treatment of major depressive disorder and generalized anxiety disorder. By inhibiting the reuptake of serotonin and norepinephrine, it helps to restore the balance of these neurotransmitters in the brain, alleviating symptoms of depression and anxiety. The labeled compound also serves as a valuable tool for researchers to study the underlying mechanisms of these disorders and develop more effective treatment strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 919514-01-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,9,5,1 and 4 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 919514-01:
(8*9)+(7*1)+(6*9)+(5*5)+(4*1)+(3*4)+(2*0)+(1*1)=175
175 % 10 = 5
So 919514-01-5 is a valid CAS Registry Number.

919514-01-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyl-2,3,4,5,6,7,8-d7-oxy)-, (γS)-

1.2 Other means of identification

Product number -
Other names Duloxetine-d7

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:919514-01-5 SDS

919514-01-5Downstream Products

919514-01-5Relevant academic research and scientific papers

SUBSTITUTED ARYLOXYPROPYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY

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Page/Page column 67, (2010/11/27)

Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized anxiety disord

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