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6-AMINO-5-(4-MORPHOLINYLMETHYL)-2(1H)-PYRIMIDINONE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

919524-54-2

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919524-54-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 919524-54-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,9,5,2 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 919524-54:
(8*9)+(7*1)+(6*9)+(5*5)+(4*2)+(3*4)+(2*5)+(1*4)=192
192 % 10 = 2
So 919524-54-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H14N4O2/c10-8-7(5-11-9(14)12-8)6-13-1-3-15-4-2-13/h5H,1-4,6H2,(H3,10,11,12,14)

919524-54-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-amino-5-(morpholin-4-ylmethyl)-1H-pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names 5-(morpholin-4-ylmethyl)cytosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:919524-54-2 SDS

919524-54-2Relevant academic research and scientific papers

C5-Morpholinomethylation of: N 1-sulfonylcytosines by a one-pot microwave assisted Mannich reaction

Mati?, Josipa,Nekola, Irena,Vi?njevac, Aleksandar,Kobeti?, Renata,Martin-Kleiner, Irena,Kralj, Marijeta,?ini?, Biserka

supporting information, p. 2678 - 2687 (2018/04/27)

A fast and efficient route for the introduction of a methylene bridged-amine (morpholinomethyl) functionality in the C5 position of the sulfonylated cytosine nucleobase has been developed. First, novel N1-sulfonylcytosine derivatives 3-6 were prepared by the condensation of silylated cytosine with selected sulfonyl chlorides. They were subsequently transformed to 5-morpholinomethyl-N1-sulfonylcytosine derivatives (8, 12-15) using microwave irradiation. As a result of cytosine ring opening in N1-tosylcytosine, depending on the reaction conditions, peculiar tosyl-urea derivative 9 has been isolated, which provided additional insight into the reaction pathway. The influence of the C5-substituent on the antiproliferative activity has been evaluated by performing the MTT test on U251, MCF-7 and MOLT-4 tumor cell-lines.

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