91960-97-3

Usage

Uses

Used in Pharmaceutical Manufacturing:
Ethanedione, bis(3-bromophenyl)is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Dye Production:
Ethanedione, bis(3-bromophenyl)is also utilized in the production of dyes, where its chemical properties contribute to the color and stability of the final product.
Used in Organic Synthesis:
Ethanedione, bis(3-bromophenyl)serves as a versatile intermediate in organic synthesis, enabling the creation of a wide range of organic compounds for various applications.
Used as a Research Chemical:
In the field of scientific research, Ethanedione, bis(3-bromophenyl)- is employed as a research chemical, aiding in the study and understanding of chemical reactions and properties of related compounds.
Used in Chemical Industry:
Ethanedione, bis(3-bromophenyl)is utilized in the chemical industry for the production of various organic compounds, contributing to the development of new materials and products.

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 204444-15-5 1,2-di-(3-bromophenyl)-1,2-ethanediol 
• 164403-02-5 1,2-bis(3-bromophenyl)-2-hydroxyethanone 

Downstream Products

• 38267-82-2 2,5-Bis-(4-bromo-phenyl)-3,4-bis-(3-bromo-phenyl)-cyclopenta-2,4-dienone 
• 38268-14-3 3,4-Bis-(3-bromo-phenyl)-2,5-diphenyl-cyclopenta-2,4-dienone 
• 1193139-06-8 bis(3-bromophenyl)glycoluril 
• 873000-48-7 C₂₀H₁₂Br₂N₂ 
• 887578-13-4 C₁₉H₁₁Br₂N₃ 
• 1505453-17-7 1,2-bis(3-(pyridin-3-yl)phenyl)ethane-1,2-dione 
• 1398565-78-0 2-(3-bromobenzoyl)-4-(3-bromophenyl)-4-oxobutanenitrile 
• 38160-46-2 1,2-bis(3-bromophenyl)-1,1,2,2-tetrafluoroethane 

Relevant academic research and scientific papers

Isostructurality of quinoxaline crystal phases: The interplay of weak hydrogen bonds and halogen bonding

Tailoring the physical properties of molecular crystals though the construction of solid solutions requires the existence of isostructural crystals. Simple substitutions of a given molecular framework can give a range of different crystal structures. A se

Synthesis and biological evaluation of novel 1,2,4-triazine derivatives bearing carbazole moiety as potent α-glucosidase inhibitors

A new series of 1,2,4-triazine derivatives bearing carbazole moiety 7a-7p were designed, synthesized, and evaluated for their α-glucosidase inhibitory activity. The majority of the screened compounds displayed potent α-glucosidase inhibitory activity, with IC50 values in the range of 4.27 ± 0.07-47.75 ± 0.25 μM as compared to the standard drug acarbose. Among the series, compound 7k represented the most potent α-glucosidase inhibitory activity with IC50 values of 4.27 ± 0.07 μM. Kinetic analysis revealed that compound 7k is a non-competitive inhibitor with a Ki of 4.43 μM. Furthermore, the binding interactions of compound 7k with α-glucosidase was confirmed through molecular docking. This study showed these 1,2,4-triazine derivatives bearing carbazole moiety as a new class of α-glucosidase inhibitors.

Poly(4-vinylimidazolium) iodides: A highly recyclable organocatalyst precursor for benzoin condensation reaction

The development of highly efficient, recyclable poly(4-vinylimidazolium) iodides (2) for the benzoin condensation reaction under mild reaction conditions is discussed: poly(4-vinyl N-heterocyclic carbene)s (3) obtained from 2 showed higher catalytic activity than monomeric 4-vinyl N-heterocyclic carbene and could be successfully recovered and reused over seven times without loss of performance. the Partner Organisations 2014.

N-heterocyclic carbene-catalyzed annulation of α-cyano-1,4-diketones with ynals

In this paper, the first stereoselective annulation reaction between r-cyano-1,4-diketones and ynals, mediated by catalytic amounts of a triazolium salt precatalyst and cocatalytic amounts of a weak carboxylate base, is disclosed. The title transformation proceeds smoothly under mild reaction conditions and generates three contiguous stereogenic centers, one of which is a quaternary acetal carbon. This reaction tolerates a wide variety of electronically distinct substituents on both reaction partners and affords privileged bicyclic scaffolds in 61-90% isolated yields and with up to 20:1 diastereomeric preference.

N-heterocyclic carbene-catalyzed annulation of α-cyano-1,4-diketones with ynals

In this paper, the first stereoselective annulation reaction between r-cyano-1,4-diketones and ynals, mediated by catalytic amounts of a triazolium salt precatalyst and cocatalytic amounts of a weak carboxylate base, is disclosed. The title transformation proceeds smoothly under mild reaction conditions and generates three contiguous stereogenic centers, one of which is a quaternary acetal carbon. This reaction tolerates a wide variety of electronically distinct substituents on both reaction partners and affords privileged bicyclic scaffolds in 61-90% isolated yields and with up to 20:1 diastereomeric preference.

One-pot synthesis benzils from aldehydes via nhc-catalyzed benzoin dimerization under metal-free conditions in water

A simple and convenient one-pot procedure is reported for the synthesis of 1,2-diketones from corresponding benzoin-type condensation reaction of aromatic aldehydes in water with N,N-dialkylbenzimidazolium salt as condensation catalyst and air as oxidizing reagent.

A recyclable, self-supported organocatalyst based on a poly(N-Heterocyclic Carbene)

We report the synthesis and catalytic activity of a polymeric imidazolium salt. In contrast to the well-known resin-supported N-heterocyclic carbenes (NHCs), the material described herein affords a polymer with NHCs orthogonally positioned along a main chain upon generation in situ. The unique structural characteristics of the corresponding poly(NHC)s enabled the materials to display catalytic activities that were similar or superior to those displayed by monomeric analogues. Moreover, the new catalyst was successfully recovered and reused with minimal loss of performance over several cycles.(Figure Presented)

Novel one-pot procedure for the synthesis of 1,2-diketones

A simple and convenient one-pot procedure is reported for the synthesis of 1,2-diketones from corresponding benzoin-type condensation reaction of aromatic aldehydes in water with N,N-dialkylbenzimidazolium salt as condensation catalyst and ferric chloride as oxidizing reagent. Copyright Taylor & Francis Group, LLC.

A novel method of synthesis of 1,2-diketones from 1,2-diols using N-bromosuccinimide

A simple and convenient procedure is reported for the synthesis of benzils and aliphatic 1,2-diketones of cyclic and open chain compounds from corresponding hydrobenzoins and 1,2-diols by refluxing with N-bromosuccinimide in carbon tetrachloride in presence or absence of pyridine.