919787-35-2Relevant academic research and scientific papers
Synthesis of chiral 3-substituted hexahydropyrroloindoline via intermolecular cyclopropanation
Song, Hao,Yang, Jun,Chen, Wei,Qin, Yong
, p. 6011 - 6014 (2007/10/03)
(Chemical Equation Presented) A new and efficient synthetic route to chiral 3-substituted hexahydropyrroloindoline 18 possessing absolute configurations in accordance with indole alkaloids has been developed from readily available L-tryptophan. The key step relies on the one-pot cascade reaction of oxazolidinone 17 with diazoester, which proceeds through intermolecular cyclopropanation, ring opening, and cyclization.
