91981-91-8Relevant academic research and scientific papers
Iron-Catalyzed Cyclization of Nitrones with Geminal-Substituted Vinyl Acetates: A Direct [4 + 2] Assembly Strategy Leading to 2,4-Disubstituted Quinolines
Zhong, Mingbing,Sun, Song,Cheng, Jiang,Shao, Ying
, p. 10825 - 10831 (2016/11/29)
An iron-catalyzed intermolecular [4 + 2] cyclization of arylnitrones with geminal-substituted vinyl acetates was developed for the synthesis of 2,4-disubstituted quinolines in moderate to good yields with good functional group compatibilities. Preliminary mechanistic studies suggest a plausible iron-catalyzed C-H activation process under external-oxidant-free conditions.
Gold-catalyzed cyclization-cycloaddition cascade reactions of allenyl acetals with nitrones
Vasu, Dhananjayan,Liu, Rai-Shung
supporting information, p. 13638 - 13641 (2013/01/15)
Gold and silver: When allenyl acetals and nitrones are treated with a catalytic amount of a gold complex and a silver salt they react through a cyclization-cycloaddition cascade reaction to give a mixture of diastereomeric tricyclic products. The mixture converges to a single product upon acid hydrolysis (see scheme). The key intermediate is postulated to be a 1-methoxyfulvene species. Copyright
A novel general method for the synthesis of nitrones by reaction of nitroso compounds with anions of aliphatic nitro compounds
Lyapkalo,Ioffe,Strelenko,Tartakovsky
, p. 856 - 862 (2007/10/03)
Anions of aliphatic nitro compounds R1R2C=NO2- react with nitroso compounds RNO to give nitrones R1R2C=N(O)R. Salts of nitro compounds with metals and Et3N, as well as trimethylsilyl nitronates in the presence of F-, can serve as the sources of the anions. The structure of the nitrones was established by NMR spectroscopy. 1,3-Dipolar cycloaddition of a series of the nitrones obtained to olefins was investigated.
THE SIMPLEST PHENYLNITRONES AND THEIR CONVERSION INTO ISOXAZOLIDINE DERIVATIVES
Zelenin, K.N.,Bezhan, I.P.,Ershov, A.Yu.
, p. 688 - 691 (2007/10/02)
Reaction of N-phenylhydroxylamine with the simplest alkanals leads initially to the formation of N-phenylnitrones, dimerization of which gives 5-substituted isoxazolidine.Taking the reactions of N-phenylnitrones, benzaldehyde, and acetone as an example, t
SYNTHESIS AND STRUCTURE OF HYDROXYISOXAZOLIDINES AND DERIVATIVES OF HYDROXYLAMINE AND ALKENALS
Zelenin, K. N.,Motorina, I. A.,Sviridova, L. A.,Bezhan, I. P.,Ershov, A. Yu.,et al.
, p. 1018 - 1024 (2007/10/02)
The reactions of N-substituted hydroxylamines with alkenals serve as a method for the synthesis of the corresponding 2-substituted 3(5)-hydroxyisoxazolidines.The reaction pathway is determined by the nature of the substituent attached to the nitrogen atom.Ring-chain isomerism has been detected in these newly obtained compounds.
