91987-74-5Relevant academic research and scientific papers
Lanthanide(III) complexes of phosphorus acid analogues of H4DOTA as model compounds for the evaluation of the second-sphere hydration
Kotkova, Zuzana,Pereira, Giovannia A.,Djanashvili, Kristina,Kotek, Jan,Rudovsky, Jakub,Hermann, Petr,Vander Elst, Luce,Muller, Robert N.,Geraldes, Carlos F. G. C.,Lukes, Ivan,Peters, Joop A.
, p. 119 - 136 (2009)
Five DOTA-like ligands lacking a water molecule in the first coordination sphere of their GdIII complexes, namely the phosphinates H 4DOTPH, H4DOTPhm and H 4DOTPEt, and the phosp
Kinetic study of dissociation of Eu(III) complex with H8dotp (H8dotp = 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylphosphonic acid))
Piskula,Svobodová,Lubal,Lis,Hnatejko,Hermann
, p. 3748 - 3755 (2007)
The dissociation kinetics of the europium(III) complex with H8dotp ligand was studied by means of molecular absorption spectroscopy in UV region at ionic strength 3.0 mol dm-3 (Na,H)ClO4 and in temperature region 25-60 °C.
14. Metal Complexes with Macrocyclic Ligands. Part XXXI. Protonation Studies and Complexation Properties of Tetraazamacrocyclic Methylenephosphonates with Earth-Alkali Ions
Delgado, Rita,Siegfried, Liselotte C.,Kaden, Thomas A.
, p. 140 - 148 (1990)
The three ligands 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylenephosphonic acid) (1), 1,4,7,11-tetraazacyclotridecane-1,4,7,11-tetrakis(methylenephosphonic acid) (2), and 1,4,8,11-tetraazacyclotetradecane-1,4,8,11-tetrakis(methylenephosphonic acid) (3) have been synthesized by condensation of the corresponding macrocycles with formaldehyde and phosphorous acid.The protonation and stability constants with the earth-alkali ions have been determined at 25 deg C and I=0.1 m (Me4N(NO3)) by potentiometric titrations.Because of the high values of the first two protonation constants, 1H-NMR measurements were necessary to determine them.Titrations in different supporting electrolytes (NaNO3, KNO3, RbNO3, CsNO3, and Me4N(NO3)) show that their choice is of paramount importance, as the above ligands can form complexes with alkali-metal ions.The potentiometric results for the earth-alkali ions show that beside mononuclear complexes of different degrees of protonation (, n=0-4), also binuclear species are formed (, m=0-2).It is interesting that 1 with the smallest macrocyclic ring has the greatest tendency to form binuclear complexes, which are so stable that they partially prevent the formation of the corresponding mononuclear species.For, , , and , the stability sequence is Mg2+ 2+ > Sr2+ > Ba2+, whereas for , , and , the stability steadily decreases from Mg2+ to Ba2+.
METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID
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Page/Page column 28, (2014/02/15)
The present invention is related to a new method for the synthesis of alpha-aminoalkylenephosphonic acid or its phosphonate esters comprising the steps of forming a reaction mixture by mixing a P-O-P anhydride moiety comprising compound, having one P-atom at the oxidation state (+111) and the other P-atom at the oxidation state (+111) or (+V), an aminoalkanecarboxylic acid and an acid catalyst, wherein said reaction mixture comprises an equivalent ratio of alpha-aminoalkylene carboxylic acid to P-O-P anhydride moieties of at least 0.2, and recovering the resulting alpha-aminoalkylene phosphonic acid compound or an ester thereof from the reaction mixture.
Improved synthesis and application of lanthanide 1,4,7,10-tetrakis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane complexes Ln(DOTP)
Swinkels, Dorine W.,Duynhoven, John P. M. van,Hilbers, Cornelis W.,Tesser, Godefridus I.
, p. 124 - 128 (2007/10/02)
Complexes of lanthanides with 1,4,7,10-tetrakis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane (DOTP) were synthesized for use as shift reagents in a study on the three-dimensional structure of the gene-5 protein encoded by Coli-phage M13.The
