920006-37-7Relevant articles and documents
Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues
Ahn, Yu Mi,Vogeti, Lakshminarayana,Liu, Chun-Jing,Santhapuram, Hari K.R.,White, Jonathan M.,Vasandani, Veena,Mitscher, Lester A.,Lushington, Gerald H.,Hanson, Paul R.,Powell, Douglas R.,Himes, Richard H.,Roby, Katherine F.,Ye, Qizhuang,Georg, Gunda I.
, p. 702 - 713 (2007)
The design and synthesis of a small library of 8-amidoflavone, 8-sulfonamidoflavone, 8-amido-7-hydroxyflavone, and heterocyclic analogues of flavopiridol is reported. The potential activity of these compounds as kinase inhibitors was evaluated by cytotoxi