92007-54-0Relevant academic research and scientific papers
Inhibitors of acyl-CoA:Cholesterol O-acyltransferase. 17. Structure-activity relationships of several series of compounds derived from N-chlorosulfonyl isocyanate
Picard, Joseph A.,O'Brien, Patrick M.,Sliskovic, Drago R.,Anderson, Maureen K.,Bousley, Richard F.,Hamelehle, Katherine L.,Krause, Brian R.,Stanfield, Richard L.
, p. 1243 - 1252 (2007/10/03)
Several series of acyl-CoA:cholesterol O-acyltransferase inhibitors were prepared by the stepwise addition of nitrogen, oxygen, and sulfur nucleophiles to N-chlorosulfonyl isocyanate. The (aminosulfonyl)ureas 3-44 were the most potent inhibitors in vitro,
Oxysulfonyl carbamates
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, (2008/06/13)
The present invention is directed to compounds of the following general Formula I, methods for using the compounds of Formula I, pharmaceutical compositions thereof, and processes for preparing the compounds. STR1 wherein X is oxygen or sulfur; wherein R
Aminosulfonyl carbamates
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, (2008/06/13)
A compound of the following general formula which is useful in treating hypocholesterolemia and atherosclerosis: STR1 wherein X is oxygen or sulfur; R is hydrogen, alkyl having from 1 to 8 carbon atoms, or benzyl; R1 is phenyl, substituted phen
SYNTHESES A L'AIDE D'HETEROCUMULENES. 4. Action L'Isocyanate De Chlorosulfonyle Sur les Phenols Encombres
Hedayatullah, Mir,Hugueny, Jean Claude
, p. 167 - 172 (2007/10/02)
The synthesis of the N-chlorosulfonylcarbamates derived from seven hindered phenols is described, as well as their hydrolysis giving a high yield of the corresponding simple carbamates, the selective substitution of their chlorine atom by the anilino radi
