92018-09-2

Upstream product

• 5390-04-5 pent-1-yn-5-ol 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 536-74-3 phenylacetylene 
• 55501-48-9 5-bromopent-4-yn-1-ol 

Downstream Products

• 1445792-69-7 3-phenylethynyl-5,6-dihydro-4H-pyrrolo[1,2-c][1,2,3]triazole 
• 20252-42-0 (E)-7-phenylhept-2-ene-4,6-diynal 
• 1379654-87-1 (Z)-7-phenylhept-2-ene-4,6-diynal 

Relevant academic research and scientific papers

Copper Catalysis for Selective Heterocoupling of Terminal Alkynes

A Cu-catalyzed selective aerobic heterocoupling of terminal alkynes is disclosed, which enables the synthesis of a broad range of unsymmetrical 1,3-diynes in good to excellent yields. The results disprove the long-held belief that homocouplings are exclusively favored in the Glaser-Hay reaction.

Copper-catalyzed cross-coupling reactions of bromoalkynols with terminal alkynes in supercritical carbon dioxide

Copper-catalyzed cross-coupling reactions of bromoalkynols and terminal alkynes were carried out in supercritical carbon dioxide (scCO2) to afford the corresponding unsymmetrical diynes with good yields. The reaction is sensitive to temperature and the pressure of CO2. Methanol, as a cosolvent of scCO2, could promote dissolution of the inorganic salt and thus facilitated the reaction. This new heterocoupling reaction system is more environmentally friendly than more traditional methods, since it uses scCO2 as solvent and sodium acetate as base instead of amines. Georg Thieme Verlag Stuttgart.

Novel pesticides, preparation and use

The specification describes and claims methods of controlling acarine pests by application of a compound of Formula (I), methods of controlling arthropod pests by application of a compound of Formula (IA), compounds of Formula (IA) per se, pesticidal compositions comprising a compound of Formula (IA), and processes for preparing a compound of Formula (IA).