920479-31-8

Basic information

• Product Name: CYCLOPROPYL-(3-FLUORO-BENZYL)-AMINE
• Synonyms: CYCLOPROPYL-(3-FLUORO-BENZYL)-AMINE;N-Cyclopropyl-3-fluorobenzylaMine, 97%
• CAS NO: 920479-31-8
• Molecular Formula: C₁₀H₁₂FN
• Molecular Weight: 165.21
• Mol File: 920479-31-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CYCLOPROPYL-(3-FLUORO-BENZYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOPROPYL-(3-FLUORO-BENZYL)-AMINE(920479-31-8)
• EPA Substance Registry System: CYCLOPROPYL-(3-FLUORO-BENZYL)-AMINE(920479-31-8)

Safety Data

• Hazardous Substances Data: 920479-31-8(Hazardous Substances Data)

Usage

General Description

CYCLOPROPYL-(3-FLUORO-BENZYL)-AMINE is a chemical compound with the molecular formula C10H13FN. It is a substituted amine with a cyclopropyl group and a 3-fluoro-benzyl group attached to the nitrogen atom. CYCLOPROPYL-(3-FLUORO-BENZYL)-AMINE has applications in organic synthesis, pharmaceutical development, and materials science. It may also be used as a building block for the preparation of various biologically active molecules and materials with specialized properties. Its specific uses and properties depend on the context and purpose for which it is being utilized.

Upstream product

• 765-30-0 Cyclopropylamine 
• 456-48-4 3-Fluorobenzaldehyde 

Relevant articles and documents

Design, Synthesis, and Structure-Activity Relationship of Economical Triazole Sulfonamide Aryl Derivatives with High Fungicidal Activity

Plant fungal diseases have caused great decreases in crop quality and yield. As one of the considerable agricultural diseases, cucumber downy mildew (CDM) caused by pseudoperonospora cubensis seriously influences the production of cucumber. Amisulbrom is a commercial agricultural fungicide developed by Nissan Chemical, Ltd., for the control of oomycetes diseases that is highly effective against CDM. However, the synthesis of amisulbrom has a high cost because of the introduction of the bromoindole ring. In addition, the continuous use of amisulbrom might increase the risk of resistance development. Hence, there is an imperative to develop active fungicides with new scaffolds but low cost against CDM. In this study, a series of 1,2,4-triazole-1,3-disulfonamide derivatives were designed, synthesized, and screened. Compound 1j showed a comparable fungicidal activity with amisulbrom, but it was low cost and ecofriendly. It has the potential to be developed as a new fungicide candidate against CDM. Further investigations of structure-activity relationship exhibited the structural requirements of 1,2,4-triazole-1,3-disulfonamide and appropriate modification in N-alkyl benzylamine groups with high fungicidal activity. This research will provide powerful guidance for the design of highly active lead compounds with a novel skeleton and low cost.