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Cyclopropanecarboxylic acid, 1-(2,4-difluorophenyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

920501-68-4

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920501-68-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 920501-68-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,0,5,0 and 1 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 920501-68:
(8*9)+(7*2)+(6*0)+(5*5)+(4*0)+(3*1)+(2*6)+(1*8)=134
134 % 10 = 4
So 920501-68-4 is a valid CAS Registry Number.

920501-68-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,4-difluorophenyl)cyclopropane-1-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:920501-68-4 SDS

920501-68-4Relevant academic research and scientific papers

Preparation method of arylcyclopropane compound

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Paragraph 0089-0093; 0104-0108, (2022/01/10)

The present invention discloses a method for preparing an arylcyclopropane compound, 1.0eq phenylacetonitrile and 1.1eq 1-bromo-2-chloroethane as the starting material, N, N- dimethylacetamide as a solvent, solvent dosage of 10V, plus 2.5eq sodium hydride

Systematic investigation of halogen bonding in protein-ligand interactions

Hardegger, Leo A.,Kuhn, Bernd,Spinnler, Beat,Anselm, Lilli,Ecabert, Robert,Stihle, Martine,Gsell, Bernard,Thoma, Ralf,Diez, Joachim,Benz, Joerg,Plancher, Jean-Marc,Hartmann, Guido,Banner, David W.,Haap, Wolfgang,Diederich, Francois

, p. 314 - 318 (2011/02/28)

Halogen bonding triggers activity: Increasing binding affinity was observed for a series of covalent human Cathepsin L inhibitors by exchanging an aryl ring H atom with Cl, Br, and I, which undergo halogen bonding with the C=O group of Gly61 in the S3 pocket of the enzyme. Fluorine, in contrast, strongly avoids halogen bonding (see scheme). The strong distance and angle dependence of halogen bonding was confirmed for biological systems. Copyright

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